Medicare local coverage
Medicare coverage for MolDX: Molecular Biomarker Testing to Guide Targeted Therapy Selection in Rheumatoid Arthritis (LCD)
4 Medicare Administrative Contractors publish a local coverage determination (LCD) for MolDX: Molecular Biomarker Testing to Guide Targeted Therapy Selection in Rheumatoid Arthritis. The snapshot lists 5 LCD records: 4 active, 1 retired.
An LCD applies only in the jurisdiction of the contractor that wrote it. Two contractors can cover the same service with different criteria, documentation requirements and covered diagnoses, so check the LCD from the contractor that processes your claims.
LCDs by contractor
| Contractor | LCD | Status | Last updated |
|---|---|---|---|
CGS Administrators, LLCMAC - Part A, MAC - Part B | L39427 | Active | Jul 2, 2026 |
Noridian Healthcare Solutions, LLCMAC - Part A, MAC - Part B | L39469 | Retired Jan 22, 2026 | Jan 22, 2026 |
Noridian Healthcare Solutions, LLCMAC - Part A, MAC - Part B | L39467 | Active | Jan 12, 2026 |
Palmetto GBAMAC - Part A, MAC - Part B | L39424 | Active | Aug 13, 2024 |
WPS Insurance CorporationMAC - Part A, MAC - Part B | L39481 | Active | Aug 1, 2025 |
An LCD marked Future has been finalized and is in its notice period; it applies from the effective date shown. LCD IDs link to the record on cms.gov.
Billing and coding articles
The codes live in the billing and coding article that goes with each LCD: the CPT and HCPCS codes the policy applies to, the ICD-10 codes that support medical necessity, and any modifier or documentation rules.
- A59484Palmetto GBAUpdated Jan 2, 2025
- A59521Noridian Healthcare Solutions, LLCUpdated Jan 12, 2026
- A59522Noridian Healthcare Solutions, LLCUpdated Jan 22, 2026
- A59529CGS Administrators, LLCUpdated Jul 31, 2025
- A59536WPS Insurance CorporationUpdated Jan 23, 2025
CMS also lists 5 response-to-comments articles for this topic, where contractors answer public comments on the proposed LCD: A59483, A59519, A59523, A59524, A59534.
Check claim lines against Medicare coverage
Coverage Check tells you whether a claim's diagnoses support Medicare LCD or NCD coverage for each procedure line, and shows the policy and CMS source behind each answer.
Related LCD topics
- MolDX: Molecular Biomarker Testing for Risk Stratification of Cutaneous Squamous Cell Carcinoma
- MolDX: Non-Next Generation Sequencing Targeted Molecular Panel Tests for Targeted Therapy in Cancer
- MolDX: Biomarker Testing in Metabolic Dysfunction-Associated Steatotic Liver Disease and Metabolic Dysfunction-Associated Steatohepatitis
- MolDX: Blood Product Molecular Antigen Typing
- MolDX: Melanoma Risk Stratification Molecular Testing
- MolDX: Molecular Assays for the Diagnosis of Cutaneous Melanoma
All Medicare LCD topics · National coverage determinations · Payer policies by payer
Source: CMS Medicare Coverage Database, via the public CMS Coverage API, snapshot Oct 25, 2026. LCDs change between snapshots; confirm the version in effect for your date of service on cms.gov before billing.