Medicare local coverage

Medicare coverage for MolDX: Molecular Biomarkers to Risk-Stratify Patients at Increased Risk for Prostate Cancer (LCD)

4 Medicare Administrative Contractors publish a local coverage determination (LCD) for MolDX: Molecular Biomarkers to Risk-Stratify Patients at Increased Risk for Prostate Cancer. The snapshot lists 5 LCD records: 4 active, 1 retired.

An LCD applies only in the jurisdiction of the contractor that wrote it. Two contractors can cover the same service with different criteria, documentation requirements and covered diagnoses, so check the LCD from the contractor that processes your claims.

LCDs by contractor

ContractorLCDStatusLast updated
CGS Administrators, LLCMAC - Part A, MAC - Part B
L38997ActiveMar 10, 2026
Noridian Healthcare Solutions, LLCMAC - Part A, MAC - Part B
L39007Retired Jan 22, 2026Jan 22, 2026
Noridian Healthcare Solutions, LLCMAC - Part A, MAC - Part B
L39005ActiveJan 12, 2026
Palmetto GBAMAC - Part A, MAC - Part B
L38985ActiveJun 25, 2025
WPS Insurance CorporationMAC - Part A, MAC - Part B
L39042ActiveJun 17, 2025

An LCD marked Future has been finalized and is in its notice period; it applies from the effective date shown. LCD IDs link to the record on cms.gov.

Billing and coding articles

The codes live in the billing and coding article that goes with each LCD: the CPT and HCPCS codes the policy applies to, the ICD-10 codes that support medical necessity, and any modifier or documentation rules.

  • A58700Palmetto GBAUpdated Jun 16, 2026
  • A58713CGS Administrators, LLCUpdated Jun 19, 2026
  • A58718Noridian Healthcare Solutions, LLCUpdated Jun 16, 2026
  • A58724Noridian Healthcare Solutions, LLCUpdated Jan 22, 2026
  • A58759WPS Insurance CorporationUpdated Jun 17, 2026

CMS also lists 5 response-to-comments articles for this topic, where contractors answer public comments on the proposed LCD: A59069, A59112, A59118, A59142, A59144.

Check claim lines against Medicare coverage

Coverage Check tells you whether a claim's diagnoses support Medicare LCD or NCD coverage for each procedure line, and shows the policy and CMS source behind each answer.

Related LCD topics

All Medicare LCD topics · National coverage determinations · Payer policies by payer

Source: CMS Medicare Coverage Database, via the public CMS Coverage API, snapshot Oct 25, 2026. LCDs change between snapshots; confirm the version in effect for your date of service on cms.gov before billing.